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How to Stop Attacking Yourself

By Mark Hyman on Wednesday January 25th, 2017

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Are You Inflamed?

Inflammation is a ‘hot’ topic in medicine. It appears connected to almost every known chronic disease — from heart disease to cancer, diabetes to obesity, autism to dementia, and even depression.

Other inflammatory diseases such as allergies, asthma, arthritis, and autoimmune disease are increasing at dramatic rates. As physicians, we are trained to shut off inflammation with aspirin, anti-inflammatory medication (such as Advil or Motrin), steroids, and increasingly more powerful immune suppressing medication with serious side effects.

But we are not trained to find and treat the underlying causes of inflammation in chronic disease. Hidden allergens, infections, environmental toxins, an inflammatory diet, and stress are the real causes of these inflammatory conditions.

Autoimmune diseases, specifically, affect 24 million people and include rheumatoid arthritis, lupus, multiple sclerosis, thyroid disease, inflammatory bowel disease, and more.

Stress is like wind to a fireAlmost all physical ailments begin with stress.

These are often addressed by powerful immune suppressing medication but don’t address the cause. That’s like taking a lot of aspirin while you are standing on a tack. The real treatment is not more aspirin or a strong immune suppressant, but removing the tack.

If you want to cool off inflammation in the body, you must find the source. Treat the fire, not the smoke. In medicine, we are mostly taught to diagnose disease by symptoms, NOT by their underlying cause.

What is Functional Medicine?

Functional medicine, the emerging 21st-century paradigm of systems medicine, teaches us to treat the cause, not only the symptoms; to ask the question WHY are you sick, not only WHAT disease do you have.

I recently participated in a group discussion with a conventional doctor, a rheumatologist, and patient with an autoimmune disease, and one of my patients who was cured of a complex autoimmune disease by addressing the causes.

Symptoms: tip of the icebergSymptoms are only the tip of the iceberg. The real issue lies beneath the surface.

The focus of the other doctors, however, was how to suppress the inflammation with medication, not finding and treating the cause. Functional medicine is a different way of thinking about diseases. It helps us understand and treat the real causes of inflammation instead of finding ways to shut down the symptoms. Medicine, as it is practised today, is like taking the battery out of a smoke detector while a fire burns down your house!

Autoimmune conditions are connected by one central biochemical process: A runaway immune response, also known as systemic inflammation, that results in your body attacking its own tissues.

When my patient described how he cured his autoimmune disease by finding and eliminating the causes of inflammation in his diet and environment, it was dismissed as a ‘spontaneous remission’. In the face of a paradigm-shattering medical case, these doctors were hardly curious and instead were quickly dismissive; simply describing it as anecdotal.

My patient on that panel, a hard-working 46-year-old father of three, was once so inflamed he could barely function. By treating the underlying causes of his inflammation, he is now in vibrant good health and enjoying his life with his kids, whom he is now fully capable of caring for.

Healthy and happy father and kidsFinding the cause of our ailments, and treating those, is how we regain our vibrancy of life.

Stories like these are not anecdotes but a giant compass, pointing us in the direction we should be looking to find answers to our health problems.

By understanding what autoimmunity is, how inflammation spirals out of control and describing some of the underlying causes of these fires in the body, autoimmune issues, ranging from allergies to arthritis, can be overcome.

Autoimmunity: What it is and How Does it Occur?

We are facing an epidemic of allergic (60 million people), asthmatic (30 million people), and autoimmune disorders (24 million people). Autoimmune diseases include rheumatoid arthritis, lupus, multiple sclerosis, psoriasis, celiac disease, thyroid disease, and the many other hard-to-classify syndromes in the 21st century.

These are all autoimmune conditions, and at their root, they are connected by one central biochemical process: a runaway immune response, also known as systemic inflammation, that results in your body attacking its own tissues.

Your immune system is your defence against invaders. It is your internal army and has to clearly distinguish friend from foe — to know you from others. Autoimmunity occurs when your immune system gets confused and your own tissues get caught in friendly cross-fire.

InvaderYour immune system detects invaders, and works to eliminate them.

Your body is fighting something — an infection, a toxin, an allergen, a food or the stress response — and somehow it redirects its hostile attack on your joints, your brain, your thyroid, your gut, your skin, or sometimes your whole body.

This immune confusion is a result of what is referred to as ‘molecular mimicry’. Conventional approaches don’t have a method for finding the insult causing the problem, however, functional medicine provides a map to find out which molecule the cells are mimicking.

Interestingly, autoimmune disorders occur almost exclusively in developed countries. People in poor nations without modern amenities like running water, flushing toilets, washing machines, and sterile backyards don’t get these diseases.

If you grew up on a farm with lots of animals, you are also less likely to have any of these inflammatory disorders. Playing in the dirt, being dirty, and being exposed to bugs and infections trains your immune system to recognize what is foreign and what is ‘you’.

Girl playing in the dirtExposure to dirt and ‘bugs’ as a child actually strengthens your immune system.

In this country, autoimmune diseases are a huge health burden. They are the eighth leading cause of death among women; shortening the average patient’s lifespan by eight years. The annual health care cost for autoimmune diseases is $120 billion a year, representing nearly twice the economic health care burden of cancer (about $70 billion a year). (i)

Unfortunately, many of the conventional treatments available can make you feel worse. Anti-inflammatory drugs like Advil, steroids, immune suppressants like methotrexate, and the new TNF-alpha blockers like Enbrel or Remicade can lead to intestinal bleeding, kidney failure, depression, psychosis, osteoporosis, muscle loss, and diabetes, not to mention overwhelming infection and cancer.(ii)


When used selectively these drugs can help people get their lives back. But they are not a long-term solution. They shouldn’t be the end of treatment, but a bridge to cool off inflammation while we treat the underlying cause of the disease.

There is another way to deal with autoimmune conditions. Here is an example.

Recovering from Autoimmunity: Addressing the Root Causes of Inflammation.

My patient, Sam, ended up on a long misadventure through the medical system before he came to see me. For years he went from doctor to doctor, getting all kinds of labels for his problems, but no real help in treating them.

This hard-working, once healthy trade professional had suddenly developed a series of inflammatory conditions, including chronic sinus and prostate infections. Many doctors gave him antibiotics for these infections.

Shortly thereafter, he developed severe chest pains and went to the emergency room. While he was there, doctors found swollen lymph nodes and told him he had lymphoma, a form of cancer. For three weeks he lived in despair until the biopsy results came back. It turned out he didn’t have cancer but an autoimmune disease. Which autoimmune disease? The doctors weren’t quite sure…

Doctors discussingNot addressing the core issue will only lead to more problems in the long term.

He had many abnormal blood test results — like low white blood cell and platelet counts, high levels of auto-antibodies of all types (antibodies that attack our own tissues), high immunoglobulins (the foot soldiers of the immune system), and autoimmune thyroid disease. But doctors had a hard time putting their finger on what was wrong. They couldn’t label him.

Meanwhile, Sam developed metabolic syndrome and weight gain (pre-diabetes) as a result of the runaway inflammation in his body. Using a functional medicine approach; a new way of thinking about the underlying causes and imbalances in chronic disease, I began by asking Sam some simple questions. Then I went hunting for toxins, allergens, and infections — all common causes of inflammation — and found the real causes of his symptoms.

He had taken so many antibiotics that altered his gut flora or bacteria and promoted yeast overgrowth. Fungus and yeast flourished in his body, growing between his toes, on his toenails, in his crotch, and scalp. He had Helicobacter pylori bacteria in his gut. He had a leaky gut and reacted to many foods, including dairy and gluten. He was exposed to toxins at his job and had high levels of mercury. And he had chronic sinus infections.

The effect of gluten on celiac intestinesAutoimmune diseases can lead to leaky gut, food intolerances, and celiac disease.

So we went to work cleaning his ‘house’. I treated his yeast with antifungals and the H. pylori with antibiotics, got rid of his food allergies, fixed his gut, detoxified him from metals, and cleaned up his sinuses.

Then I helped heal his immune system by supporting it with nutrients – zinc, fish oil, vitamin D, herbs, and probiotics, and put him on a clean, whole-foods, allergen-free, anti-inflammatory diet.

At his next follow-up visit, he was feeling a lot better. His memory, concentration, and energy levels were all much better, and he’d lost weight. When his labs came in, they confirmed this — they were all back to normal. His white cells had increased and his immune markers had calmed way down.

Sam’s results simply reflect the application of a new model of thinking about problems, called functional medicine — a way to get to the root of health problems and treat the underlying causes of what ails you, instead of suppressing symptoms with medications.

Fresh fruit and vegetablesA healthy and wholesome diet is an important part of maintaining our health.

If you have an autoimmune disease, here is what you need to think about and do.

Nine Steps to Treating An Autoimmune Disease:

  1. Check for hidden infections — yeast, viruses, bacteria, Lyme, etc. — with the help of a doctor, and treat them.
  2. Check for hidden food allergens with IgG food testing or just try The UltraSimple Diet, which is designed to eliminate most food allergens.
  3. Get tested for celiac disease, which is a blood test that any doctor can do.
  4. Get checked for heavy metal toxicity. Mercury and other metals can cause autoimmunity.
  5. Fix your gut. For details, see my blog on irritable bowel syndrome.
  6. Use nutrients such as fish oil, vitamin C, vitamin D, and probiotics to help calm your immune response naturally.
  7. Exercise regularly — it’s a natural anti-inflammatory.
  8. Practice deep relaxation like yoga, deep breathing, biofeedback, or massage, because stress worsens the immune response.
  9. Have an understanding of Functional Medicine, that addresses the underlying cause of disease.

Give these steps a try and you will likely start feeling less inflamed. The answers are right in front of you. Treat the underlying causes of your illness and you will begin to experience vibrant health once more.

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Words By Mark Hyman

Originally posted on Dr Hyman

 

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References

(i) Nakazawa, D. (2008). The Autoimmune Epidemic. Simon & Schuster. New York.

(ii) Siegel, C.A., Marden, S.M., Persing, S.M., et al. (2009). Risk of lymphoma associated with combination anti-tumor necrosis factor and immunomodulator therapy for the treatment of Crohn’s disease: a meta-analysis. Clin Gastroenterol Hepatol. 7(8): 874-81.

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